| League | 88 | 40 | 15 | 33 | 145 | 125 | |
| Others | 4 | 3 | 0 | 1 | 5 | 2 | |
| Total | 92 | 43 | 15 | 34 | 150 | 127 |
| League | 81 | 34 | 15 | 32 | 130 | 120 | |
| Others | 1 | 1 | 0 | 0 | 1 | 0 | |
| Total | 82 | 35 | 15 | 32 | 131 | 120 |
| Saturday 14 March 1992 | ||
| League Division One | ||
| Bramall Lane (30,183) | ||
| Sheff Utd | 1 - 2 | Man Utd |
| McClair Blackmore | ||
| Starting XI | ||
| Peter Schmeichel Paul Parker Denis Irwin Steve Bruce Mike Phelan Gary Pallister Bryan Robson Paul Ince Brian McClair Lee Sharpe Andrei Kanchelskis | ||
| Substitutes | ||
| Clayton Blackmore | ||
| Managers | ||
| Dave Bassett | Alex Ferguson | |
| Peter Schmeichel | 28 | 41 | |
| Paul Parker | 28 | 34 | |
| Denis Irwin | 26 | 91 | |
| Steve Bruce | 31 | 203 | |
| Mike Phelan | 29 | 115 | |
| Gary Pallister | 27 | 149 | |
| Bryan Robson | 35 | 414 | |
| Paul Ince | 24 | 122 | |
| Brian McClair | 28 | 248 | |
| Lee Sharpe | 21 | 100 | |
| Andrei Kanchelskis | 23 | 32 | |
| Clayton Blackmore | 27 | 221 | |
| average age | 27 | - | |
| 1 | Sat 17 Aug 1991 | League Division One | MU | 2 - 0 | Notts County | Old Trafford | |
| 2 | Wed 21 Aug 1991 | League Division One | Aston Villa | 0 - 1 | MU | Villa Park | |
| 3 | Sat 24 Aug 1991 | League Division One | Everton | 0 - 0 | MU | Goodison Park | |
| 4 | Wed 28 Aug 1991 | League Division One | MU | 1 - 0 | Oldham Athletic | Old Trafford | |
| 5 | Sat 31 Aug 1991 | League Division One | MU | 1 - 1 | Leeds United | Old Trafford | |
| 6 | Tue 3 Sep 1991 | League Division One | Wimbledon | 1 - 2 | MU | Selhurst Park | |
| 7 | Sat 7 Sep 1991 | League Division One | MU | 3 - 0 | Norwich City | Old Trafford | |
| 8 | Sat 14 Sep 1991 | League Division One | Southampton | 0 - 1 | MU | The Dell | |
| 9 | Wed 18 Sep 1991 | European Cup Winners Cup | Athinaikos | 0 - 0 | MU | Apostolos Nikolaidis | |
| 10 | Sat 21 Sep 1991 | League Division One | MU | 5 - 0 | Luton Town | Old Trafford | |
| 11 | Wed 25 Sep 1991 | League Cup | MU | 3 - 0 | Cambridge United | Old Trafford | |
| 12 | Sat 28 Sep 1991 | League Division One | Tottenham Hotspur | 1 - 2 | MU | White Hart Lane | |
| 13 | Wed 2 Oct 1991 | European Cup Winners Cup | MU | 2 - 0 | Athinaikos | Old Trafford | |
| 14 | Sun 6 Oct 1991 | League Division One | MU | 0 - 0 | Liverpool | Old Trafford | |
| 15 | Wed 9 Oct 1991 | League Cup | Cambridge United | 1 - 1 | MU | Abbey Stadium | |
| 16 | Sat 19 Oct 1991 | League Division One | MU | 1 - 1 | Arsenal | Old Trafford | |
| 17 | Wed 23 Oct 1991 | European Cup Winners Cup | Athletico Madrid | 3 - 0 | MU | Vincente Calderon | |
| 18 | Sat 26 Oct 1991 | League Division One | Sheffield Wednesday | 3 - 2 | MU | Hillsborough | |
| 19 | Wed 30 Oct 1991 | League Cup | MU | 3 - 1 | Portsmouth | Old Trafford | |
| 20 | Sat 2 Nov 1991 | League Division One | MU | 2 - 0 | Sheffield United | Old Trafford | |
| 21 | Wed 6 Nov 1991 | European Cup Winners Cup | MU | 1 - 1 | Athletico Madrid | Old Trafford | |
| 22 | Sat 16 Nov 1991 | League Division One | Manchester City | 0 - 0 | MU | Maine Road | |
| 23 | Tue 19 Nov 1991 | European Super Cup | MU | 1 - 0 | Red Star Belgrade | Old Trafford | |
| 24 | Sat 23 Nov 1991 | League Division One | MU | 2 - 1 | West Ham United | Old Trafford | |
| 25 | Sat 30 Nov 1991 | League Division One | Crystal Palace | 1 - 3 | MU | Selhurst Park | |
| 26 | Wed 4 Dec 1991 | League Cup | MU | 2 - 0 | Oldham Athletic | Old Trafford | |
| 27 | Sat 7 Dec 1991 | League Division One | MU | 4 - 0 | Coventry City | Old Trafford | |
| 28 | Sun 15 Dec 1991 | League Division One | Chelsea | 1 - 3 | MU | Stamford Bridge | |
| 29 | Thu 26 Dec 1991 | League Division One | Oldham Athletic | 3 - 6 | MU | Boundary Park | |
| 30 | Sun 29 Dec 1991 | League Division One | Leeds United | 1 - 1 | MU | Elland Road | |
| 31 | Wed 1 Jan 1992 | League Division One | MU | 1 - 4 | Queens Park Rangers | Old Trafford | |
| 32 | Wed 8 Jan 1992 | League Cup | Leeds United | 1 - 3 | MU | Elland Road | |
| 33 | Sat 11 Jan 1992 | League Division One | MU | 1 - 0 | Everton | Old Trafford | |
| 34 | Wed 15 Jan 1992 | FA Cup | Leeds United | 0 - 1 | MU | Elland Road | |
| 35 | Sat 18 Jan 1992 | League Division One | Notts County | 1 - 1 | MU | Meadow Lane | |
| 36 | Wed 22 Jan 1992 | League Division One | MU | 1 - 0 | Aston Villa | Old Trafford | |
| 37 | Mon 27 Jan 1992 | FA Cup | Southampton | 0 - 0 | MU | The Dell | |
| 38 | Sat 1 Feb 1992 | League Division One | Arsenal | 1 - 1 | MU | Highbury | |
| 39 | Wed 5 Feb 1992 | FA Cup | MU | 2 - 2 | Southampton | Old Trafford | |
| 40 | Sat 8 Feb 1992 | League Division One | MU | 1 - 1 | Sheffield Wednesday | Old Trafford | |
| 41 | Sat 22 Feb 1992 | League Division One | MU | 2 - 0 | Crystal Palace | Old Trafford | |
| 42 | Wed 26 Feb 1992 | League Division One | MU | 1 - 1 | Chelsea | Old Trafford | |
| 43 | Sat 29 Feb 1992 | League Division One | Coventry City | 0 - 0 | MU | Highfield Road | |
| 44 | Wed 4 Mar 1992 | League Cup | Middlesbrough | 0 - 0 | MU | Ayresome Park | |
| 45 | Wed 11 Mar 1992 | League Cup | MU | 2 - 1 | Middlesbrough | Old Trafford | |
| 46 | Sat 14 Mar 1992 | League Division One | Sheffield United | 1 - 2 | MU | Bramall Lane | |
| 47 | Wed 18 Mar 1992 | League Division One | Nottingham Forest | 1 - 0 | MU | City Ground | |
| 48 | Sat 21 Mar 1992 | League Division One | MU | 0 - 0 | Wimbledon | Old Trafford | |
| 49 | Sat 28 Mar 1992 | League Division One | Queens Park Rangers | 0 - 0 | MU | Loftus Road | |
| 50 | Tue 31 Mar 1992 | League Division One | Norwich City | 1 - 3 | MU | Carrow Road | |
| 51 | Tue 7 Apr 1992 | League Division One | MU | 1 - 1 | Manchester City | Old Trafford | |
| 52 | Sun 12 Apr 1992 | League Cup | MU * | 1 - 0 | Nottingham Forest | Wembley | |
| 53 | Thu 16 Apr 1992 | League Division One | MU | 1 - 0 | Southampton | Old Trafford | |
| 54 | Sat 18 Apr 1992 | League Division One | Luton Town | 1 - 1 | MU | Kenilworth Road | |
| 55 | Mon 20 Apr 1992 | League Division One | MU | 1 - 2 | Nottingham Forest | Old Trafford | |
| 56 | Wed 22 Apr 1992 | League Division One | West Ham United | 1 - 0 | MU | Upton Park | |
| 57 | Sun 26 Apr 1992 | League Division One | Liverpool | 2 - 0 | MU | Anfield | |
| 58 | Sat 2 May 1992 | League Division One | MU | 3 - 1 | Tottenham Hotspur | Old Trafford |
In the tables above and below, where MU * (or NH *) appears in the home team column, it indicates a match played at a neutral venue.
| 1 | Sat 25 Nov 1893 | League Division One | Sheffield United | 3 - 1 | NH | Bramall Lane | |
| 2 | Sat 10 Mar 1894 | League Division One | NH | 0 - 2 | Sheffield United | Bank Street | |
| 3 | Sat 15 Sep 1906 | League Division One | Sheffield United | 0 - 2 | MU | Bramall Lane | |
| 4 | Sat 19 Jan 1907 | League Division One | MU | 2 - 0 | Sheffield United | Bank Street | |
| 5 | Sat 21 Sep 1907 | League Division One | MU | 2 - 1 | Sheffield United | Bank Street | |
| 6 | Sat 18 Jan 1908 | League Division One | Sheffield United | 2 - 0 | MU | Bramall Lane | |
| 7 | Sat 10 Oct 1908 | League Division One | MU | 2 - 1 | Sheffield United | Bank Street | |
| 8 | Sat 13 Feb 1909 | League Division One | Sheffield United | 0 - 0 | MU | Bramall Lane | |
| 9 | Sat 23 Oct 1909 | League Division One | Sheffield United | 0 - 1 | MU | Bramall Lane | |
| 10 | Sat 5 Mar 1910 | League Division One | MU | 1 - 0 | Sheffield United | Old Trafford | |
| 11 | Sat 10 Dec 1910 | League Division One | Sheffield United | 2 - 0 | MU | Bramall Lane | |
| 12 | Sat 15 Apr 1911 | League Division One | MU | 1 - 1 | Sheffield United | Old Trafford | |
| 13 | Sat 9 Dec 1911 | League Division One | MU | 1 - 0 | Sheffield United | Old Trafford | |
| 14 | Sat 13 Apr 1912 | League Division One | Sheffield United | 6 - 1 | MU | Bramall Lane | |
| 15 | Sat 7 Dec 1912 | League Division One | MU | 4 - 0 | Sheffield United | Old Trafford | |
| 16 | Sat 12 Apr 1913 | League Division One | Sheffield United | 2 - 1 | MU | Bramall Lane | |
| 17 | Sat 22 Nov 1913 | League Division One | Sheffield United | 2 - 0 | MU | Bramall Lane | |
| 18 | Wed 22 Apr 1914 | League Division One | MU | 2 - 1 | Sheffield United | Old Trafford | |
| 19 | Sat 12 Dec 1914 | League Division One | MU | 1 - 2 | Sheffield United | Old Trafford | |
| 20 | Sat 17 Apr 1915 | League Division One | Sheffield United | 3 - 1 | MU | Bramall Lane | |
| 21 | Sat 25 Oct 1919 | League Division One | Sheffield United | 2 - 2 | MU | Bramall Lane | |
| 22 | Sat 1 Nov 1919 | League Division One | MU | 3 - 0 | Sheffield United | Old Trafford | |
| 23 | Sat 6 Nov 1920 | League Division One | MU | 2 - 1 | Sheffield United | Old Trafford | |
| 24 | Sat 13 Nov 1920 | League Division One | Sheffield United | 0 - 0 | MU | Bramall Lane | |
| 25 | Mon 2 Jan 1922 | League Division One | Sheffield United | 3 - 0 | MU | Bramall Lane | |
| 26 | Mon 17 Apr 1922 | League Division One | MU | 3 - 2 | Sheffield United | Old Trafford | |
| 27 | Sat 12 Dec 1925 | League Division One | MU | 1 - 2 | Sheffield United | Old Trafford | |
| 28 | Sat 24 Apr 1926 | League Division One | Sheffield United | 2 - 0 | MU | Bramall Lane | |
| 29 | Mon 30 Aug 1926 | League Division One | Sheffield United | 2 - 2 | MU | Bramall Lane | |
| 30 | Sat 1 Jan 1927 | League Division One | MU | 5 - 0 | Sheffield United | Old Trafford | |
| 31 | Sat 10 Dec 1927 | League Division One | Sheffield United | 2 - 1 | MU | Bramall Lane | |
| 32 | Sat 21 Apr 1928 | League Division One | MU | 2 - 3 | Sheffield United | Old Trafford | |
| 33 | Tue 25 Dec 1928 | League Division One | MU | 1 - 1 | Sheffield United | Old Trafford | |
| 34 | Wed 26 Dec 1928 | League Division One | Sheffield United | 6 - 1 | MU | Bramall Lane | |
| 35 | Mon 7 Oct 1929 | League Division One | Sheffield United | 3 - 1 | MU | Bramall Lane | |
| 36 | Sat 3 May 1930 | League Division One | MU | 1 - 5 | Sheffield United | Old Trafford | |
| 37 | Sat 22 Nov 1930 | League Division One | Sheffield United | 3 - 1 | MU | Bramall Lane | |
| 38 | Sat 28 Mar 1931 | League Division One | MU | 1 - 2 | Sheffield United | Old Trafford | |
| 39 | Sat 1 Sep 1934 | League Division Two | Sheffield United | 3 - 2 | MU | Bramall Lane | |
| 40 | Sat 5 Jan 1935 | League Division Two | MU | 3 - 3 | Sheffield United | Old Trafford | |
| 41 | Sat 19 Oct 1935 | League Division Two | MU | 3 - 1 | Sheffield United | Old Trafford | |
| 42 | Sat 22 Feb 1936 | League Division Two | Sheffield United | 1 - 1 | MU | Bramall Lane | |
| 43 | Sat 2 Oct 1937 | League Division Two | MU | 0 - 1 | Sheffield United | Old Trafford | |
| 44 | Thu 17 Feb 1938 | League Division Two | Sheffield United | 1 - 2 | MU | Bramall Lane | |
| 45 | Sat 12 Oct 1946 | League Division One | Sheffield United | 2 - 2 | MU | Bramall Lane | |
| 46 | Mon 26 May 1947 | League Division One | MU | 6 - 2 | Sheffield United | Maine Road | |
| 47 | Sat 13 Sep 1947 | League Division One | MU | 0 - 1 | Sheffield United | Maine Road | |
| 48 | Sat 31 Jan 1948 | League Division One | Sheffield United | 2 - 1 | MU | Bramall Lane | |
| 49 | Sat 18 Sep 1948 | League Division One | Sheffield United | 2 - 2 | MU | Bramall Lane | |
| 50 | Wed 4 May 1949 | League Division One | MU | 3 - 2 | Sheffield United | Maine Road | |
| 51 | Sat 5 Dec 1953 | League Division One | MU | 2 - 2 | Sheffield United | Old Trafford | |
| 52 | Sat 24 Apr 1954 | League Division One | Sheffield United | 1 - 3 | MU | Bramall Lane | |
| 53 | Sat 13 Nov 1954 | League Division One | Sheffield United | 3 - 0 | MU | Bramall Lane | |
| 54 | Sat 2 Apr 1955 | League Division One | MU | 5 - 0 | Sheffield United | Old Trafford | |
| 55 | Sat 10 Sep 1955 | League Division One | Sheffield United | 1 - 0 | MU | Bramall Lane | |
| 56 | Sat 14 Jan 1956 | League Division One | MU | 3 - 1 | Sheffield United | Old Trafford | |
| 57 | Mon 23 Apr 1962 | League Division One | MU | 0 - 1 | Sheffield United | Old Trafford | |
| 58 | Tue 24 Apr 1962 | League Division One | Sheffield United | 2 - 3 | MU | Bramall Lane | |
| 59 | Sat 1 Dec 1962 | League Division One | Sheffield United | 1 - 1 | MU | Bramall Lane | |
| 60 | Sat 20 Apr 1963 | League Division One | MU | 1 - 1 | Sheffield United | Old Trafford | |
| 61 | Sat 30 Nov 1963 | League Division One | Sheffield United | 1 - 2 | MU | Bramall Lane | |
| 62 | Mon 13 Apr 1964 | League Division One | MU | 2 - 1 | Sheffield United | Old Trafford | |
| 63 | Sat 26 Dec 1964 | League Division One | Sheffield United | 0 - 1 | MU | Bramall Lane | |
| 64 | Mon 28 Dec 1964 | League Division One | MU | 1 - 1 | Sheffield United | Old Trafford | |
| 65 | Sat 20 Nov 1965 | League Division One | MU | 3 - 1 | Sheffield United | Old Trafford | |
| 66 | Sat 16 Apr 1966 | League Division One | Sheffield United | 3 - 1 | MU | Bramall Lane | |
| 67 | Mon 26 Dec 1966 | League Division One | Sheffield United | 2 - 1 | MU | Bramall Lane | |
| 68 | Tue 27 Dec 1966 | League Division One | MU | 2 - 0 | Sheffield United | Old Trafford | |
| 69 | Sat 14 Oct 1967 | League Division One | Sheffield United | 0 - 3 | MU | Bramall Lane | |
| 70 | Sat 20 Apr 1968 | League Division One | MU | 1 - 0 | Sheffield United | Old Trafford | |
| 71 | Sat 2 Oct 1971 | League Division One | MU | 2 - 0 | Sheffield United | Old Trafford | |
| 72 | Tue 4 Apr 1972 | League Division One | Sheffield United | 1 - 1 | MU | Bramall Lane | |
| 73 | Sat 30 Sep 1972 | League Division One | Sheffield United | 1 - 0 | MU | Bramall Lane | |
| 74 | Mon 23 Apr 1973 | League Division One | MU | 1 - 2 | Sheffield United | Old Trafford | |
| 75 | Wed 26 Dec 1973 | League Division One | MU | 1 - 2 | Sheffield United | Old Trafford | |
| 76 | Sat 2 Mar 1974 | League Division One | Sheffield United | 0 - 1 | MU | Bramall Lane | |
| 77 | Sat 23 Aug 1975 | League Division One | MU | 5 - 1 | Sheffield United | Old Trafford | |
| 78 | Sat 13 Dec 1975 | League Division One | Sheffield United | 1 - 4 | MU | Bramall Lane | |
| 79 | Sun 11 Mar 1990 | FA Cup | Sheffield United | 0 - 1 | MU | Bramall Lane | |
| 80 | Sat 17 Nov 1990 | League Division One | MU | 2 - 0 | Sheffield United | Old Trafford | |
| 81 | Tue 26 Feb 1991 | League Division One | Sheffield United | 2 - 1 | MU | Bramall Lane | |
| 82 | Sat 2 Nov 1991 | League Division One | MU | 2 - 0 | Sheffield United | Old Trafford | |
| 83 | Sat 14 Mar 1992 | League Division One | Sheffield United | 1 - 2 | MU | Bramall Lane | |
| 84 | Sat 15 Aug 1992 | Premiership | Sheffield United | 2 - 1 | MU | Bramall Lane | |
| 85 | Sat 6 Feb 1993 | Premiership | MU | 2 - 1 | Sheffield United | Old Trafford | |
| 86 | Sun 14 Feb 1993 | FA Cup | Sheffield United | 2 - 1 | MU | Bramall Lane | |
| 87 | Wed 18 Aug 1993 | Premiership | MU | 3 - 0 | Sheffield United | Old Trafford | |
| 88 | Tue 7 Dec 1993 | Premiership | Sheffield United | 0 - 3 | MU | Bramall Lane | |
| 89 | Sun 9 Jan 1994 | FA Cup | Sheffield United | 0 - 1 | MU | Bramall Lane | |
| 90 | Mon 9 Jan 1995 | FA Cup | Sheffield United | 0 - 2 | MU | Bramall Lane | |
| 91 | Sat 18 Nov 2006 | Premiership | Sheffield United | 1 - 2 | MU | Bramall Lane | |
| 92 | Tue 17 Apr 2007 | Premiership | MU | 2 - 0 | Sheffield United | Old Trafford |